I'm not too sure about life changing, but I have a few favourites.
Enders Game by Orson Scott Card. Ive reread the entire series 3 times, and Enders Game itself about 6 times. I fell in love with Ender reading that book.
American Gods by Neil Gaiman. Probably my all time favourite book by my all time favourite author. Even if that book completely ruined me from eating KFC ever again.
Not a life changing book, but definitely a favourite is Everything Is Illuminated by Jonathan Safran Foer. I've never laughed so hard in my life than when I read it. Definitely got a few strange stares reading this on the bus and laughing so hard I cant breathe. Not for grammar nazis.
The most recent read that has stuck with me was The Boy In the Striped Pajamas. Not 100% sure what the authors name is but a beautiful book nonetheless. I cried for an hour when I finished it and read it cover to cover with short food breaks in between.