I am a PMS sufferer. Taking the pill did not work at all for me. As a matter of fact, it made some of my symptoms much worse. I finally found the right specialist to help me with it. I take natural progesterone from day 12 to day 27 (there is a gradual drop at the end) in order to feel somewhat "normal" during those days. Without it, I was irrational, couldn't concentrate, had suicidal thoughts, was forgetful, etc, all starting as early as day 12. With the progesterone in my system, I can be much more "stable" as Master Evan puts it. If I miss doses, the symptoms increase. In order for us to get through this every month, each morning I e-mail Master Evan with what day of my cycle it is. As the days pass and the end of my cycle approaches, I still have a harder time coping. With these daily reports, Master Evan can be a calming force in my life as well as direct my duties towards things I am better able to handle. This helps me to not feel unworthy of him, and helps us both not get so frustrated. And if I know I am off a dose or two (4 times a day can be hard to remember) I tell him and let him know I am feeling I am a bit unstable, and he helps me through that, too.
Another key part of my PMS treatment is diet. It is imperative that I have a small amount of protein every 3 hours or so to keep my blood sugar level, and try to keep sugar intake low. This helps keep my emotions much more even. It can be a few almonds, a bit of cheese, a couple of peanut buttered crackers... Nothing big, but very, very important. If you can't find a medication that works, and can't find a doctor willing to prescribe natural progesterone, at least give the diet a try. You'd be surprised how much of a difference it can make. Good luck to you!