I'm agnostic and my wife is nominally Catholic. Religion has never gotten in the way of anything here. We both respect each other's houses of worship; when she wants to go to Mass, I go with her; when I go to Fry's Electronics she comes with me.
Seriously, we rarely attend Mass except when she feels troubled. I wouldn't dream of not being with her when she's like that, despite feeling a tad out-of-place amid the Faithful. Personally, I find Churches to be very peaceful, serene places, a welcome pause from the hectic world, and we both always leave feeling better.